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[68Ga]Ga-HSA-ICG
- Development stage
- Preclinical
- Lead developer
- Advanced Centre for Treatment, Research and Education in Cancer
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Recombinant Proteins and Enzymes, Nanoparticles → Drug Delivery Systems
- Administration
- Intradermal, Subcutaneous
01
Overview
[68Ga]Ga-HSA-ICG is a hybrid, dual-modality diagnostic imaging agent consisting of human serum albumin (HSA) nanocolloids radiolabeled with the positron emitter Gallium-68 ([68Ga]) and conjugated with the near-infrared fluorescent dye Indocyanine Green (ICG). Developed by researchers at the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, and Amity University, this agent is designed for sentinel lymph node imaging and mapping. By combining high-resolution PET imaging with real-time intraoperative fluorescence guidance in a single injection, [68Ga]Ga-HSA-ICG aims to improve the accuracy of sentinel lymph node detection and surgical resection.
- Other names
- 68Ga-HSA-ICG[68Ga]Ga-HSA nanocolloid-ICGGallium-68 Labeled Human Serum Albumin Nanocolloids Conjugated with Indocyanine GreenGallium68 Labeled Human Serum Albumin Nanocolloids Conjugated with Indocyanine GreenGallium 68 Labeled Human Serum Albumin Nanocolloids Conjugated with Indocyanine Green
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